Select Manuscripts

  1. Alisafaei F, Mandal K, Saldanha R, Swoger M, Yang H, Shi X, Guo M, Hehnly H, Castañeda CA, Janmey PA, Patteson AE, Shenoy VB. (2024) Vimentin is a key regulator of cell mechanosensing through opposite actions on actomyosin and microtubule networks. Commun Biol. 2024 PMID: 38811770

  2. Saldanha R, Ho Thanh MT, Krishnan N#, Hehnly H, Patteson A. (2024). Vimentin supports cell polarization by enhancing centrosome function and microtubule acetylation. J R Soc Interface. PMID: 38835244

  3. Chakraborty A, Dutta A, Dettori LG, Daoud R, Li J, Gonzalez I, Xue X, Hehnly H, Sung P, Bah A, Feng W. Complex interplay between FMRP and DHX9 during DNA replication stress. JBC 2023.

  4. Campana MB, Davis TR, Novak SX, Cleverdon ER, Bates M, Krishnan N, Curtis ER, Childs MD, Pierce MR, Morales-Rodgriguez Y, Sieburg MA, Hehnly H, Luyt LG, Hougland JL. Cellular uptake of a fluorescent ligand reveals Ghrelin O-acyltransferase interacts with extracellular peptides and exhibits unexpected localization for a secretory pathway enzyme. ACS Chem Biol. 2023. PMID:37494676

  5. Aljiboury A*, Eric Ingram*, Nikhila Krishnan*, Favour Ononiwu*, Debadrita Pal*, Julie Manikas, Christopher Taveras, Nicole Hall, Jonah Da Silva, Judy Freshour, and Heidi Hehnly. Rab8-, Rab11-, and Rab35-dependent mechanisms coordinating lumen and cilia formation during Left-Right Organizer development. PLOS Genetics. 2023 *equal contributions. PMID: 37186603

  6. Aljiboury A, Mujcic A, Curtis E, Cammerino T, Magny D, Lan Y, Bates M, Freshour J, Ahmed-Braimeh YH, Hehnly H. Pericentriolar matrix (PCM) integrity relies on Cenexin and Polo-Like Kinase (PLK)1. Molecular Biology of the Cell. 2022. PMID:35609215

  7. Krishnan N, Swoger M, Rathbun LI, Fioramonti PJ, Freshour J, Bates M, Patteson AE, Hehnly H. Rab11 endosomes and Pericentrin coordinate centrosome movement during pre-abscission in vivo. Life Sci Alliance. 2022. PMID:35304423

  8. Swoger M, Gupta S, Charrier EE, Bates M, Hehnly H, Patteson AE. Vimentin Intermediate Filaments Mediate Cell Morphology on Viscoelastic Substrates. ACS App Bio Mater. 2022. PMID:3499547

  9. Riley JF, Fioramonti PJ, Rusnock AK, Hehnly H, Castaneda CA. ALS-Linked mutations impair UBQLN2 stress-induced bimolecular condensate assembly in cells. J Neurochem. 2021. PMID:34129687

  10. Rathbun L, Aljiboury A, Bai X, Hall NA, Manikas J, Amack JD, Bembenek JN, Hehnly H, PLK1- and PLK4-mediated asymmetric mitotic centrosome size and positioning in the early zebrafish embryo. Current Biology. 2020

  11. Rathbun L, Colicino E, Manikas J, O’Connell J, Krishnan N, Reilly N, Coyne S, Erdemci-Tandogan G, Garrastegui A, Freshour J, Santra P, Manning ML, Amack J, Hehnly H. Cytokinetic Bridge Triggers De Novo Lumen Formation In Vivo. Nature Communications. 2020

  12. Bucko PJ, Lombard CK, Rathbun L, Garcia I, Bhat A, Wordeman L, Smith FD, Maly DJ, Hehnly H, Scott JD. Subcellular drug targeting illuminates local kinase action. Elife. 2019 Dec 24;8. PMID:31872801

  13. Colicino EG, Stevens K, Curtis E, Rathbun L, Bates M, Manikas J, Amack J, Freshour J, Hehnly H. Chromosome misalignment is associated with PLK1 activity at cenexin-positive mitotic centrosomes. Molecular Biology of the Cell. 2019 PMID:31042116 *Awarded Cover

  14. Dao TP, Martyniak B, Canning AJ, Lei Y, Colicino EG, Cosgrove MS, Hehnly H, Castañeda CA. ALS-Linked Mutations Affect UBQLN2 Oligomerization and Phase Separation in a Position- and Amino Acid-Dependent Manner. Structure. 2019

  15. Dao TP, Kolaitis RM, Kim HJ, O'Donovan K, Martyniak B, Colicino E, Hehnly H, Taylor JP, Castañeda CA. Ubiquitin Modulates Liquid-Liquid Phase Separation of UBQLN2 via Disruption of Multivalent Interactions. Molecular Cell. 2018

  16. Colicino EG, Garrastegui AM, Freshour J, Santra P, Post DE, Kotula L, Hehnly H. Gravin regulates centrosome function through PLK1. Molecular Biology of the Cell. 2018

  17. Taneja N, Fenix AM, Rathbun L, Millis BA, Tyska MJ, Hehnly H, Burnette DT. Focal adhesions control cleavage furrow shape and spindle tilt during mitosis. Scientific Reports 2016

  18. Vertii A, Ivshina M, Zimmerman W, Hehnly H, Kant S, Doxsey S. The Centrosome Undergoes Plk1-Independent Interphase Maturation during Inflammation and Mediates Cytokine Release. Developmental Cell 2016

  19. Hung H, Hehnly H¥, Doxsey S¥. The mother centriole protein, cenexin, modulates symmetric lumen formation through spindle orientation. Current Biology 2016 (¥) depicts co-corresponding author

  20. Hehnly H*, Canton D*, Bucko P, Langeberg LK, Ogier L, Gelman I, Santana LF, Wordeman L, Scott JD.  An Aurora A-Plk1 kinase scaffold depleted in testicular seminomas impacts mitotic spindle orientation in germline stem cells. eLIFE. 2015  (*) depicts co-first authorship

  21. Elisa de Souza E, Hehnly H, Perez AM, Vaz Meirelles G, Costa Smetana JH, Doxsey S, Kobarg J., Human Nek7-interactor RGS2 is required for mitotic spindle organization. Cell Cycle. 2015 Feb 9:0. [Epub ahead of print] PMID: 25664600

  22. Chen CT*, Hehnly H*, Yu Q*, Farkas D, Zheng G, Redick SD, Hung HF, Samtani R, Jurczyk A, Akbarian S, Wise C, Jackson A, Bober M, Guo Y, Lo C, Doxsey S. A unique set of centrosome proteins requires pericentrin for spindle-pole localization and spindle orientation. Current Biology. 2014 2014 Oct 6;24(19):2327-34. PMID: 25220058  (*) depicts co-first authorship   *Current Biology Commentary titled “Pericentrin: critical for spindle orientation.”

  23. Hehnly H and Doxsey S, Rab11 endosomes contribute to mitotic spindle organization and orientation. Developmental Cell. 2014 Mar 10;28(5):497-507. PMID: 24561039 *Awarded Cover Image. *Developmental Cell Commentary titled “Spindlegate: the biological consequences of disrupting traffic.”

  24. Hehnly H, Chen CT, Powers C, Lui HL, and Doxsey S, The Centrosome regulates the Rab11-dependent recycling endosome pathway at appendages of the mother centriole. Current Biology. 2012 Oct 23; 22(20):1944-50. PMID: 22981775 *Featured in Faculty 1000 *Featured in Nature Reviews Molecular Cell Biology

  25. Hehnly H, Xu W, Chen J, and Stamnes M (2010) Cdc42 regulates microtubule-dependent Golgi positioning. Traffic. 11(8): 1067-78; PMID: 20525016 *Awarded Cover Image.

  26. Hehnly H, Longhini K, Chen J, and Stamnes M (2009) Retrograde Shiga toxin trafficking is regulated by ARHGAP21 and Cdc42. Molecular Biology of the Cell. 20(20):4303-12 PMID: 19692570

  27. Hehnly H, Sheff D, Stamnes M (2006) Shiga toxin facilitates its retrograde transport by modifying microtubule dynamics. Molecular Biology of the Cell. 17(10): p.4379-89 PMID: 16885418

SELECT PREPRINTS

  1. Manna RK, Retzlaff EM, Hinman AM, Lan Y#, Abdel-Razek O, Bates M%, Hehnly H, Amack JD, Manning ML. Dynamical forces drive organ morphology changes during embryonic development. bioRxiv. 2024 Jul 17:2024.07.13.603371. doi: 10.1101/2024.07.13.603371. PMID: 39071435

  2. Yan Wu, Yiling Lan*, Favour Ononiwu*, Abigail Poole, Kirsten Rasmussen, Jonah Da Silva, Abdalla W. Shamil, Li-En Jao, and Heidi Hehnly, Temporal and anteriorly positioned mitotic zones drive asymmetric microtubule patterns needed for Left-Right Organizer development. bioRxiv, 2024.05.12.593765 (2024).

  3. Aljiboury A*, Eric Ingram*, Nikhila Krishnan*, Favour Ononiwu*, Debadrita Pal*, Julie Manikas, Christopher Taveras, Nicole Hall, Jonah Da Silva, Judy Freshour, and Heidi Hehnly. Rab8-, Rab11-, and Rab35-dependent mechanisms coordinating lumen and cilia formation during Left-Right Organizer development. BioRxiv. 2022 *equal contributions. 10.31.514532. doi:10.1101/2022.10.31.514532

  4. Aljiboury A, Mujcic A, Curtis E, Cammerino T, Magny D, Lan Y, Bates M, Freshour J, Ahmed Y, Hehnly H (2022) Pericentriolar matrix integrity relies on cenexin and Polo-Like Kinase (PLK)1. bioRxiv 2022.01.09.475500; doi: https://doi.org/10.1101/2022.01.09.475500 

  5. Krishnan N, Swoger M, Bates M, Freshour J, Fioramonti PJ, Patteson AE, Hehnly H (2021) Rab11 endosomes coordinate centrosome number and movement following mitotic exit. bioRxiv 2021.08.11.455966; doi: https://www.biorxiv.org/content/10.1101/2021.08.11.455966v1

  6. Rathbun LI, Aljiboury AA, Bai X, Manikas J, Amack JD, Bembenek JN, Hehnly H (2020) PLK1- and PLK4-medicated asymmetric mitotic centrosome size and positioning in the early zebrafish embryo. bioRxiv doi: https://doi.org/10.11010/2020.04.13.039362

    **preLights commentary from The Company of Biologists by Maiko Kitaoka entitled “Big spot, little spot: How an asymmetric pair of mitotic centrosomes mediates early cell divisions in zebrafish”

    **Featured in April in preprints by The Node

SELECT REVIEWS/COMMENTARIES/PERSPECTIVES