Hehnly Lab has a paper at Molecular Biology of the Cell!

Colicino et al. talks about the role of Gravin anchoring PLK1 at mitotic centrosomes. This anchor is important for regulating centrosome organization and function as seen below with super resolution imaging of the centrosome component CEP215 disorganization when Gravin is lost. 

A panel taken from Figure 4 from Colicino et al. of CEP215 disorganization primarily at a single mitotic spindle pole with Gravin loss.  We argue this is through uncontrolled phosphorylation of CEP215 by PLK1 in the absence of Gravin.

Look at the Beautiful Paper!

The Hehnly Lab recently got to help with a story from Dylan Burnette's laboratory that came out in Scientific Reports. Check it out here. It is filled with beautiful microscopy and looks at the relationship between how a dividing cell communicates with an extracellular matrix, and its affect on cleavage furrow morphology, and spindle orientation.

Congrats Ana and Alison on the article titled "New frontiers: discovering cilia‐independent functions of cilia proteins"

The two lives of the centrosome during the cell cycle (A) In interphase, the centrosome functions as a basal body for primary cilia formation. (B) The basal body matures into the spindle poles during mitosis. (C) The centrosome duplicates once per cell cycle, during S phase, and moves to opposite sides of the cell starting at G2 and throughout mitosis. In G0, the centrosome docks at the membrane and templates cilia formation once again.

Ana and Alison have just published a fun review talking about the role of cilia proteins outside of the cilia. Take a peak here: Vertii A et al. EMBO Reports.